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胰激肽原酶(Kallidinogenase)

更新时间：2026-02-27

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产品详情

产品名称：胰激肽原酶(Kallidinogenase)

产品分类：动物提取物

CAS号： 9001-01-8

药典：英国药典

级别：药用级

主要销售市场：西欧,亚洲

产品描述：

胰激肽原酶，存在于哺乳动物胰腺等器官及尿液分泌物中，是激肽体系中的一个组成部分，又称血管舒缓素或胰激肽释放酶，从动物胰腺中提取的一种蛋白水解酶，属蛋白水解酶类。由18中氨基酸和4种糖所组成，分子量26800。有扩张血管、改善血液循环和微循环以及防止血栓形成的作用

Kallidinogenase, which exists in organs and urine secretions such as the mammalian pancreas, is an integral part of the antipeptide system, also known as angiosososotic or pancreatic peptide release enzyme, a proteolytic enzyme extracted from the animal pancreas, which is a proteolytic enzyme. Consisting of 18 amino acids and 4 kinds of sugars, molecular weight 26800. Has the effect of dilating blood vessels, improving blood circulation and microcirculation, and preventing thrombosis.

公司简介

江西浩然生物制药有限公司（原“江西浩然生物医药有限公司”和“南昌市浩然生物医药有限公司”）成立于2008年2月，主要从事人尿活性物质、动物脏器有效成分的开发、生产、经营。公司采用独创的生产工艺，利用先进的生化分离技术已经开发了绒促性素、尿促性素、尿促卵泡素、尿激酶、乌司他丁、糜蛋白酶、胰激肽原酶、肝素系列产品等生物医药原料及中间体，是一家集研发、生产及国内外贸易于一体的国家高新技术企业。浩然公司有6条原料药生产线，3条制剂生产线，生产基地严格按新版GMP及国际先进的欧盟cGMP设计与建设，并已形成较为完善的药品生产质量管理体系。

该公司其他产品

低分子量肝素（LMW-Heparine）

低分子量肝素由天然肝素分离或是降解得到。临床用于预防手术后血栓栓塞、预防深静脉血栓形成、肺栓塞、血液透析时体外循环的抗凝剂、末梢血管病变等。低分子量肝素是低分子量肝素钠盐，通过从猪肉肠道粘液中分离肝素的硝基酸脱聚而获得。作为一种新的抗血栓类，低分子量肝素钠在预防或治疗剂量下施用时提供立即和持续的抗血栓活性。它用于预防血液透析期间凝血和预防深静脉血栓（DVT）。浩然生物制药可供应具有以下规格的散装低分子量肝素钠。各种规格的产品也可以根据客户的要求进行准备。 Dalteparin Sodium (Low Molecular Weight Heparin Sodium) (LMWH-Na) is the sodium salt of Low Molecular Weight Heparin obtained by nitrous acid depolymerization of heparin from pork intestinal mucosa. As a new antithrombotic class, Dalteparin Sodium provides immediate and sustained antithrombotic activity when administered in prophylactic or therapeutic dosage. It is indicated for prevention of clotting during hemodialysis and prophylaxis of Deep Venous Thrombosis (DVT). Haoran Biopharma can supply bulk Dalteparin Sodium with the following specifications. Products of various specifications can also be prepared according to customers' requests. Appearance White or almost white powder Clarity of solution Clear Anti-factor Xa activity 110AXa IU/mg ~ 210AXa IU/mg Anti-factor IIa activity 35 AIIa IU/mg-100 AIIa IU/mg The ratio of anti-factor Xa to anti-factor IIa 1.9 ~ 3.2 Sodium 9.5% ~ 12.5% Range of molecular weight 8000: 15.0% ~ 25.0% Mass-average molecular mass 5600 ~ 6400 pH 5.5 ~ 8.0 Nitrite Not more than 5ppm Nitrogen 1.5% ~ 2.5% Heavy metals Not more than 30ppm Loss on drying Not more than 5.0% Nucleotide and protein impurities of the source material Pass Boron Not more than 1ppm Bacterial endotoxins Not more than 0.01IU/AXaIU

肝素钠（Heparin Sodium）

肝素钠是粘多糖硫酸酯类抗凝血药。肝素钠是由猪或牛的肠粘膜中提取的硫酸氨基葡聚糖的钠盐，属粘多糖类物质。为抗凝血药。对凝血过程的许多环节都有影响，可延长凝血时间和凝血酶原时间。本品不论在体内或体外，都有迅速的抗凝血作用。本品主要作用于纤维蛋白的形成，也可使血小板聚集减少。　　本品可用于预防和治疗血栓栓塞性疾病，如：心肌梗塞、肺栓塞、脑血管栓塞、外周静脉血栓等，可防止血栓的形成和扩大。还可用于DIC的早期，及其它体内外的抗凝。早期应用可以防止纤维蛋白原和凝血因子的耗竭。也可在输血时代替枸橼酸盐或体外循环时作为体外抗凝血药。Heparin Sodium is a viscose polysaccharides anticoagulant. Sodium heparin is a sodium salt extracted from the intestinal mucosa of pigs or cattle, and is a viscous polysaccharides. For anticoagulants. It has an effect on many aspects of the clotting process, prolonging the time of coagulation and the time of the clotting enzyme. This product, whether in the body or outside, has a rapid anticoagulant effect. This product mainly acts on the formation of fibrin, but also can reduce platelet aggregation. 　　This product can be used to prevent and treat thrombosis embolism diseases, such as: myocardial infarction, pulmonary embolism, cerebrovascular embolism, peripheral venous thrombosis, etc., to prevent the formation and expansion of blood clots. It can also be used in the early stages of DIC, and other anticoagulants inside and outside the body. Early applications prevent the depletion of fibrinogen and coagulation factors. It can also be used as an in vitro anticoagulant in the form of an in vitro anticoagulant in the form of an in vitro blood transfusion instead of hydrochlorite or in vitro circulation.

依诺肝素钠（Enoxaparin heparin）

依诺肝素钠是由来源于猪肠粘膜的肝素钠经成盐、酯化后得到的肝素-苯索氯铵盐的苄基酯衍生物在碱性条件下发生beta-消除反应裂解生成的低分子肝素钠，其主要特征为在糖链的非还原末端具有4—烯醇毗喃糖酸，在糖链的还原末端具有1，6一脱水结构，后者占全部糖的15—25%。本品主要用于预防深静脉血栓形成及肺栓塞；治疗已形成的静脉血栓；预防血液透析时体外循环中血栓的形成；治疗不稳定性心绞痛和非Q波心梗。浩然生物可以供应以下规格的依诺肝素钠原料。也可以根据客户的需求准备其他规格的产品白色或类白色粉末, 具引湿性溶解性易溶于水鉴别 A. 得到的图谱与依诺肝素钠的CRS相似 B. 抗Xa因子和抗IIa因子活性的比值: 3.3-5.3 重均分子量范围在3800和5000之间 C. 分子量低于2000的链的百分比: 12.0％～20.0％分子量在2000和8000之间的链的百分比： 68.0％～82.0％ D. 显钠盐的鉴别A反应溶液性状（10% w/v溶液）溶液澄清，颜色不得比最相近颜色的6号标准比色液更深 pH (10% w/v 溶液) 6.2～7.7 吸光系数（干燥品） 14.0～20.0 氮（干燥品） 1.5%～2.5% 钠（干燥品） 11.3%～13.5% 重金属 ≤30ppm 干燥失重 ≤10.0% 硫酸根离子与羧酸根离子的摩尔比 ≥1.8 细菌内毒素不多于0.01 EU/1 IU 抗Xa因子活性效价测定（干燥品）抗Xa因子活性：90 IU-125 IU/mg 抗IIa因子活性：20.0 IU-35.0 IU/mg 抗Xa因子和抗IIa因子活性的比值： 3.3-5.3 苯甲醇 ≤0.1%(m/m) 残留乙醇 ≤5000 ppm 微生物计数试验总需氧微生物计数：≤1000cfu/g 总联合酵母/霉菌计数：100cfu/g 指定微生物测试大肠埃希氏菌：没有检测到/g Enoxaparin sodium is the sodium salt of a low-molecular-mass heparin that is obtained by alkaline depolymerisation of the benzyl ester derivative of heparin from porcine intestinal mucosa. The majority of the components have a 4-enopyranose uronate structure at the nonreducing end of their chain It is mainly indicated for the prophylaxis of Deep Venous Thrombosis (DVT) and pulmonary embolism, treatment of venous thrombosis, prevention of clotting during hemodialysis, treatment of unstable angina and non-Q-wave myocardial infarction. Haoran Biopharma can supply bulk Enoxaparin Sodium with the following specifications. Products of various specifications can also be prepared according to customers' requests. Appearance White or almost white powder, hygroscopic Solubility Freely soluble in ** Identification A. The spectrum obtained is similar to enoxaparin sodium CRS B. The ratio of Anti-factor Xa activity to anti-factor IIa activity: 3.3-5.3 The mass-average relative molecular mass ranges between 3800 and 5000 C. The mass percentage of chains lower than 2000：12.0%～20.0% The mass percentage of chains between 2000 and 8000: 68.0%～82.0% D. It gives reaction (a) of sodium Appearance of solution (10% solution w/v) The solution is clear and not more intensely coloured than intensity 6 of the range of reference solutions of the most appropriate colour pH (10% W/V solution) 6.2～7.7 Specific absorbance (dried substance) 14.0～20.0 Nitrogen (dried substance) 1.5%～2.5% Sodium (dried substance) 11.3%～13.5% Heavy metals ≤30ppm Loss on drying ≤10.0% Molar ratio of sulfate ions to carboxylate ions ≥1.8 Bacterial endotoxins N.M.T. 0.01 EU/1 IU anti-factor Xa activity Assay (dried substance) Anti-factor Xa activity: 90 IU-125 IU/mg Anti-factor IIa activity: 20 IU-35 IU/mg The ratio of anti-factor Xa activity to anti-factor IIa activity: 3.3～5.3 Benzyl alcohol ≤0.1% (m/m) Residual ethanol ≤5000 ppm Microbial enumeration tests Total aerobic microbial count: ≤1000cfu/g Total combined yeast/moulds count: 100cfu/g Test for specified micro-organisms Escherichia coli: not detected/g

产品名称	价格	供应商	操作
胰激肽原酶	面议	宁波林叶生物科技有限公司	立即询盘
胰激肽原酶	面议	北京格源天润生物技术有限公司	立即询盘
胰激肽原酶	面议	常州千红生化制药股份有限公司	立即询盘
胰激肽原酶	面议	四川德博尔制药有限公司	立即询盘
胰激肽原酶(Pancrease Kallikrein)	面议	北京天时力搏科技发展有限公司	立即询盘
胰激肽释放酶	面议	杭州鼎燕化工有限公司	立即询盘
胶原蛋白	面议	烟台东诚药业集团股份有限公司	立即询盘
提纯蜂胶	面议	河南省维康蜂业有限公司	立即询盘
胰蛋白酶动物提取物	面议	润城生物科技（厦门）有限公司	立即询盘
硫酸软骨素	面议	烟台瑞康达生化制品有限公司	立即询盘

江西浩然生物制药有限公司

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江西省南昌市高新技术产业开发区尤口路369号

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胰激肽原酶(Kallidinogenase)

产品详情

产品描述：

公司简介

该公司其他产品

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